Displaying 1 - 20 of 121 in total
The YWHAG Ultra-Rare Mutation: A Family Hunts for Solutions
When Andrew Miner’s son James was diagnosed with an ultra-rare YWHAG mutation, the path forward was anything but clear. In this compelling episode of Sounds of Science...
Laboratory Biosecurity for Exotic Viruses
From hantavirus to Ebola to cyclosporiasis, it’s hard to escape the news about outbreaks of exotic viruses in people. How might these diseases impact or be transmitte...
From Cell Painting to Toxicology: Advancing Treatment for PACS2 Therapy
What happens when parents refuse to accept a one percent chance? In this episode of Sounds of Science, Piotr and Gosia Kosla share how their daughter Lena’s ultra‑rare...
A New Era for FOXG1: The Race to First‑in‑Human Trials
FOXG1 Research Foundation CEO Nasha Fitter returns to Sounds of Science with extraordinary updates: FDA Fast Track designation, IND clearance, and the first‑ever clini...
Norecopa: A Global 3Rs Research Database Resides in Norway
The 3Rs of animal research (Replacement, Reduction, Refinement) are truly a global effort. One of the experts leading this effort is veterinarian Adrian Smith, Secreta...
Pac-Man Chemistry: A Breakthrough in Treating Methamphetamine Overdose
What if one shot could reverse a meth overdose? In this episode of Sounds of Science, we explore CS1103 - Clear Scientific's breakthrough therapy with FDA Fast Track s...
CEO Jim Foster Reflects on his Remarkable 50 years at Charles River
We are joined by retiring CEO Jim Foster to discuss his 50 year career at Charles River. Through his decades in the industry, Foster has seen it all - from the shift t...
Finding Hope in the Rare: Jane’s Story and the Fight for Mowat-Wilson Syndrome Research
In this episode of Sounds of Science, Lauren and Matt Noonan share their powerful journey following their daughter Jane’s diagnosis with Mowat-Wilson Syndrome. From un...
From Research to Regulatory: The Career of Dr. Namandjé Bumpus
I am joined by Charles River's newest Senior Vice President, Chief Scientific & Innovation Officer Dr. Namandjé Bumpus to discuss her amazing career. From hands on res...
Bringing Dialysis to Remote Regions: Chris Atwater and the Bridge of Life
Patients who need kidney dialysis live all over the world - even in some of the remotest regions. They need updated equipment, trained healthcare staff, and lots of cl...
Hope in Action: Fighting SPG50 and Beyond with Elpida Therapeutics
When Terry Pirovolakis learned his son had an ultra-rare neurodegenerative disease, SPG50, he refused to accept “no options.” What started as a desperate search for ho...
Turning Hope Into Action: Fighting USP7-Related Diseases
What happens when a rare disease diagnosis turns life upside down? In this episode of Sounds of Science, host Mary Parker sits down with Bo Bigelow, Amber Freed, and D...
Beyond The Diagnosis
When Patricia Weltin’s daughters were diagnosed with Ehlers-Danlos Syndrome after years of uncertainty, she turned her frustration into a global movement. In this epis...
Planning For Potential Pandemics: The Coalition for Epidemic Preparedness Innovations
As we all learned in 2020, getting ahead of the next major pandemic is a matter of global concern. For the Coalition for Epidemic Preparedness Innovations, or CEPI (ce...
Breathing New Life into Toxicology: Human-Relevant Models in Action
What if we could predict how chemicals affect human lungs without using animals? In this episode of Sounds of Science, Mary McElroy, Head of Discovery Toxicology and P...
Fighting For Liam - The Leston's Story
For this episode I am joined by Megan and JC Leston, two parents who are fighting for their son Liam. The oldest of their five children, Liam was born with the rare Cr...
Choosing Wisely: The Ethics, Science, and Emotion Behind Species Selection
What if one decision could make or break your drug’s success? Join Charles River’s Sarah Gould as she unpacks the high-stakes, emotion-filled world of species selectio...
Supporting Mental Health for Veterans and First Responders: A Sabbatical Story
Charles River scientist Nicole Hoekstra, herself a US Navy veteran, used her employer-supported sabbatical to help out local Oklahoma based nonprofit Inner Circle Ment...
Little Monsters: How Microbes Manage At The Edge of Existence
Ryan Cox from Microbial Solutions joins us to discuss the curious creatures living at the edges of life – from microbes pulled from the MIR space station to antibiotic...
From Mystery to Medicine: The Science Behind a Mother’s Search
When Dalila Sabaredzovic’s sons were diagnosed with an ultra-rare genetic condition, she faced more questions than answers. But through resilience, advocacy, and the p...