Displaying 31 - 60 of 98 in total
Ep. 67: A Rare Diagnosis
Molly Dupre, a lab assistant at Charles River's Reno site, was recently diagnosed with Niemann-Pick Type B/ Acid Sphingomyelinase Deficiency. After years of waiting, d...
Ep. 66: When Drug Candidates Miss the Mark: Off-Target Liability
Senior Principal Scientific Advisor Stan Spence joins me to discuss off-target liability: what happens when a drug misses its target? What are the risks to the patient...
BONUS: Life After Cancer With Rachel and Susan
Rachel Kiserow and Susan Desmond have joined us year after year as part of Eureka's Breast Cancer Roundtable. This year, they wanted to share what happens after - afte...
Ep. 65: The New England Compounding Center Tragedy
For this episode, I am joined by Charles River's Doug Botkin and Pure Microbiology's Abby Roth to discuss the 2012 NECC meningitis outbreak. Doug and Abby bring their ...
Ep. 64: State of Oncology Report
Charles River experts Justin Bryans and Elizabeth Anderson join me for a spirited discussion of where we are now in oncology research. Could we ever see a world withou...
Ep. 63: Gene Therapy Manufacturing: Two Perspectives
Manufacturing gene therapies is a hot topic in the pharma field, on both the supplier and the client ends. Joining me to discuss this issue is Charles River Associate ...
Ep. 62: The Value of N-of-1 Research
Dr. Lauren Black and Dr. Monkol Lek are both committed to the research and advancement of rare disease treatments. But when you are trying to treat just one patient, w...
Ep. 61: Michael Hakeem on Recruiting Diversity Globally
Through his own first-hand experience, Charles River Senior Director of Global Talent Acquisition Michael Hakeem knows the importance of diversity in hiring. He joins ...
Ep. 60: From Development to Manufacturing in Biologics
Jesse McCool from Wheeler Bio and Ian Wyllie from Charles River's RightSource℠ program join me to discuss the manufacturing of biologics from both ends: getting from d...
Ep. 59: Fungal Zombies, Fact and Fiction
Mycologist Ziva Abraham discusses fungal detection and identification in cleanrooms, and whether the TV show The Last of Us portrays a realistic fungal zombie apocalypse.
Ep. 58: How To Be A Good Ally At Work
This month I am joined by Romaine Wright, Program Manager for Learning and Development for Charles River, to discuss allyship in the workplace. How can we use whatever...
Ep. 57: Elise Lewis' Career in Toxicology
This month I am joined by Dr. Elise Lewis, principal director of toxicology for Charles River's Horsham, Pennsylvania site.
Ep. 56: In Vitro Vs. In Vivo
In vivo models have been the drug safety standard for as long as there have been drug safety standards. With mounting data proving the worth of in vitro models, could ...
Ep. 55: Looking Back at 75 Years of Charles River
This year Charles River celebrated its 75th anniversary. To help me reminisce about how far the company and science in general have come in that time, I invited Chief ...
Ep. 54: Avian Flu in 2022
This year saw the worst spread of avian influenza yet, with fall showing another surge as migratory birds make their way south for the winter. Could an avian influenza...
Ep. 53: Dr. Faqi - From Scientist to Ambassador
I am joined by a very special guest - Dr. Ali Said Faqi, former employee of Charles River and current Congressman for Somalia. In 2013 his career path changed when he ...
Ep. 52: A Royal Recognition for Mental Health
Charles River senior account manager Brad Gartland experienced a great personal tragedy when his father took his own life in 2016. Driven by the loss, Brad worked to e...
Ep. 51: Gene Therapy with Dr. Kathrin Meyer
Dr. Kathrin Meyer from the Center for Gene Therapy at Nationwide Children's Hospital joins me to discuss the current state of gene therapy research - where we are now,...
Ep. 50: COVID, Monkeypox, and Avian Flu: Viruses 2022
I am joined by consulting physician Dr. Peter Matos, an expert on viral spread through his work at the U.S. Department of Defense Global Emerging Infection Surveillanc...
Ep. 49: Sex Parity in Animal Research
Sex discrimination is not just something that happens with people. In many animal studies, males have historically been used more often than females, resulting in a si...
Ep. 48: Lab Animal Diets and Doing Good Science
Graham Tobin is one of the most noted experts on laboratory animal diets, writing several definitive texts on the subject. He joins me to discuss how a lack of attenti...
Ep. 47: Killing Tumors From the Inside Out
We talk with Oliver Jonas, the Scientific Founder of Kibur Medical, about his research on implantable devices designed to distribute cancer drugs directly into tumors....
Ep. 46: Three Young Women Battle ALS and Stereotypes
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a degenerative neurological disease most often associated with older while males. However, ...
Ep. 45: A Possible Cure for Diabetes
Dr. Jeffrey Millman joins me and my colleague Laura Gee to discuss his work on a potential cure for Type 1 diabetes. Laura, who is herself a Type 1 diabetes patient, s...
Ep. 44: Vaccine Vials and COVID Innovations
Lawrence Ganti, president of SiO2 Materials Science, joins me to discuss ramping up production of his innovative vaccine vials to distribute COVID-19 vaccines. We also...
Ep. 43: Two Pioneers in HIV Activism and Research
For World AIDS Day, I interviewed two pioneers in AIDS activism and research: Dr. Kenneth Mayer, Medical Research Director of Fenway Health and a professor of medicine...
Ep. 42: Neuroscience During COVID: A Conversation With Two Scientists
This year's Society for Neuroscience meeting was supposed to be in person, but with COVID cases still high, moved to virtual. Charles River scientists Carina Peritore ...
Ep. 41: Is There a Human Lyme Vaccine on the Horizon?
With global warming affecting the tick population, the time is right to try again with a human Lyme disease vaccine. I talk with Dr. Richard Marconi, professor at Virg...
Ep. 40: Boosting the Signal for Vaccines
In this episode, I speak with Dr. Peter Matos about vaccine boosters past and present. We discuss a brief history of vaccine booster research, how we arrived at the cu...
Ep. 39: Marcus Gerald – From Patient to Scientist
Scientist Marcus Gerald experienced first hand what it feels like to be a patient at a young age. Now he helps children by researching the Developmental and Reproducti...